Achievements

2010”Nb2009”Nb2008”Nb2007b2006b2005b2004b2003
2002b2001b2000 1999b1998b1997

2010

  1. Ito T, Nuriya M and Yasui M.
    "Regulation of Kv2.1 phosphorylation in an animal model of anoxia."
    Neurobiology of Disease. in press.
  2. Kobayashi K, Kadohira I, Tanaka M, Yoshimura Y, Ikeda K, Yasui M.
    "Expression and Distribution of Tight Junction Proteins in Human Amnion During Late Pregnancy."
    Placenta. in press
  3. Hirano A, Shiraki K, Niikura T, Arakawa T, Kita Y
    "Structure changes of natively disordered Hmanin in the presence of lipid"
    Int J Biol Macromol. In press
  4. Arakawa T, Hirano A, Shiraki K, Kita Y, Koyama AH.
    "Stabilizing and destabilizing effects of arginine on deoxyribonucleic acid."
    Int J Biol Macromol. in press
  5. Arakawa T, Futatsumori-Sugai M, Tsumoto K, Kita Y, Sato H, Ejima D.
    "MEP HyperCel chromatography II: Binding, washing and elution."
    Protein Expr Purif. in press
  6. Yukutake Y, Yasui M.
    "Regulation of water permeability through aquaporin-4."
    Neuroscience. in press
  7. Hirano Y, Okimoto N, Yasuoka K, Taiji M, Suematsu M, and Yasui M
    "Molecular Mechanisms How Mercury Inhibits Water Permeation of Aquaporin-1: Understanding by Molecular Dynamics Simulation "
    Biophys J. in press
  8. Nuriya M and Yasui M.
    "Membrane potential dynamics of axons in cultured hippocampal neurons probed by second harmonic generation imaging"
    Journal of Biomedical Optics. in press.
  9. Kobayashi K, Suzuki T, Nomoto Y, Tada Y, Miyake M, Hazama A, Wada I, Nakamura T, Omori K.
    "A tissue-engineered trachea derived from a framed collagen scaffold, gingival fibroblasts and adipose-derived stem cells."
    Biomaterials. 2010 Mar 25. [Epub ahead of print]

£PAGETOP

2009

  1. Arimitsu T, Nuriya M, Ikeda K, Takahashi T, Yasui M.
    "Activity-dependent regulation of HCN1 protein in cortical neurons."
    Biochem Biophys Res Commun. 2009 387(1), 87-91.
  2. Tatsumi K, Tsuji S, Miwa H, Morisaku T, Nuriya M, Orihara M, Kaneko K, Okano H, Yasui M.
    "Drosophila big brain does not act as a water channel, but mediates cell adhesion."
    FEBS Lett. 2009 583(12), 2077-82.
  3. Narumi S, Muroya K, Abe Y, Yasui M, Asakura Y, Adachi M, and Hasegawa T
    "TSHR Mutations as a Cause of Congenital Hypothyroidism in Japan: a Population-Based Genetic Epidemiology Study."
    J. Clin. Endocrinol. Metab. 2009 94, 1317-1323
  4. Samani K, Wu G, Ai T, Shuraih M, Li Z, Purevjav E, Xi Y, Mathuria NS, Sohma Y, Towbin JA, Cheng J, Vatta M
    "A novel SCN5A mutation V1340I in Brugada Syndrome augmenting arrhythmias during febrile illness."
    Heart Rhythm 2009 6(9): 1318-1326
  5. Akamatsu K, Shibata MA, Ito Y, Sohma Y, Azuma H, Otsuki Y
    "Riluzole induces apoptotic cell death in human prostate cancer cells via endoplasmic reticulum stress."
    Anticancer Res. 2009 29(6): 2195-2204.
  6. Tsai MF, Shimizu H, Sohma Y, Li M, Hwang TC
    "State-dependent modulation of CFTR gating by pyrophosphate."
    J. Gen. Physiol. 2009 133: 405-419
  7. Hayashi MK, Tang C, Verpelli C, Narayanan R, Stearns MH, Xu RM, Li H, Sala C, Hayashi Y.
    "The postsynaptic density proteins Homer and Shank form a polymeric network structure."
    Cell. 2009 137(1):159-71.
  8. Ikeshima-Kataoka H, Wada A, Ishiwata K, Watanabe N, Saito S:
    "Cloning and Expression of cDNA for Interleukin 4 from the MSKR Inbred Strain of Mus musculus molossinus."
    IN VIVO 2009 23(2): 277-280
  9. Okano, W., Nomoto, Y., Wada, I., Kobayashi, K., Miyake, M., Nakamura, T. and Omori, K.
    "Bioengineered trachea with fibroblasts in a rabbit model."
    Annals of Otology, Rhinology & Laryngology 2009, 118, 796-804.
  10. Arakawa T, Niikura T, Arisaka F, Kita Y.
    "Short neuroprotective peptides, ADNF9 and NAP, are structurally disordered and monomeric in PBS."
    Int J Biol Macromol. 2009 45(1):8-11.
  11. Arisaka F, Arakawa T, Niikura T, Kita Y
    "Active form of Neuroprotective Humanin, HN, and inactive analog, S7A-HN, are monomeric and disorderd in aqueous phosphate solution at pH 6.0; No correlation of solution structure with activity"
    Protein Pept. Lett. 2009 16(2) 132-7
  12. Arakawa T, Kita Y, Ejima D.
    "Stress-free chromatography: IEC and HIC."
    Curr Pharm Biotechnol. 2009 4:461-3.
  13. Arakawa T, Kita Y, Koyama H
    "Synergistic virus inactivation effects of arginine"
    Biotechnology J. 2009 4, 174-178
  14. Arakawa T, Kita Y, Sato H, Ejima D.
    "Stress-free chromatography: affinity chromatography."
    Curr Pharm Biotechnol. 2009 4:456-60.
  15. Arakawa T, Kita Y, Sato H, Ejima D, MEP
    "choromatography of antibody and Fc-fusion protein using aqueous arginine solution, Protein Expr."
    Purif., 2009, 63(2) 158-63
  16. Yukutake Y, Hirano Y, Suematsu M, Yasui M.
    "Rapid and reversible inhibition of aquaporin-4 by zinc."
    Biochemistry. 2009 48(51):12059-61.
  17. Kobayashi, K., Inai, T., Shibata, Y. and Yasui, M.
    "Dynamic changes in amniotic tight junctions during pregnancy. "
    Placenta 2009, 30, 840-847.M
  18. W. Liu, C. Deng, K. Merrett, C. R. McLaughlin, P. Fagerholm, SN. S. Lagali, B. Heyne, J.C. Scaiano, M. A. Watsky, Y. Kato, R. Munger, N. Shinozaki, F. Li and M. Griffith
    "Collagen-phosphorylcholine interpenetrating network hydrogels as corneal substitutes"
    Biomaterials 30: 1551-1559, 2009

£PAGETOP

2008

  1. Kadohira I, Abe Y, Nuriya M, Sano K, Tsuji S, Arimitsu T, Yoshimura Y, Yasui M.
    "Phosphorylation in the C-terminal domain of Aquaporin-4 is required for Golgi transition in primary cultured astrocytes."
    Biochem Biophys Res Commun. 2008, 377(2), 463-8.
  2. Thomas GM, Lin DT, Nuriya M, Huganir RL.
    "Rapid and bi-directional regulation of AMPA receptor phosphorylation and trafficking by JNK."
    EMBO J. 2008, 27(2), 361-72.
  3. Abe Y, Kita Y, and Niikura T
    "Mammalian Gup1, a homolog of Saccharomyces cerevisiae glycerol uptake/transporter 1, acts as a negative regulator for N-terminal palmitoylation of Sonic hedgehog."
    FEBS J. 2008 275, 318-331
  4. Mio K, Ogura T, Mio M, Shimizu H, Hwang TC, Sato C, Sohma Y.
    "Three-dimensional reconstruction of human cystic fibrosis transmembrane conductance regulator chloride channel revealed an ellipsoidal structure with orifices beneath the putative transmembrane domain."
    J. Biol. Chem. 2008 283: 30300 - 30310
  5. Mori Y, Yoshida H, Miyamoto M, Sohma Y, Kubota T
    "Constitutive activity of inwardly rectifying K+ channel at physiological [Ca]i is mediated by Ca2+/CaMK II pathway in opossum kidney proximal tubule cells."
    J. Physiol. Sci.2008 58: 199 - 207
  6. Wu X, Yang Y, Gui P, Sohma Y, Meininger GA, Davis GE, Braun AP, Davis MJ.
    "Potentiation of BK channels by 5 1 integrin activation in arteriolar smooth muscle."
    J Physiol. 2008 586(6): 1699 - 1713
  7. Ikeshima-Kataoka H, Yuasa S:
    "Selective ablation of an astroglial subset by toxic gene expression driven by tenascin promoter."
    Neurological Research, 30(7): 701-709, 2008.
  8. Ikeshima-Kataoka H, Shen J, Eto Y, Saito S, Yuasa S:
    "Alteration of inflammatory cytokine production in the injured central nervous system of tenascin-deficient mice."
    IN VIVO 2008 22(4): 409-414.
  9. Omori, K., Tada, Y., Suzuki, T., Nomoto, Y., Matsuzuka, T., Kobayashi, K., Nakamura, T., Kanemaru, S., Yamashita, M. and Asato, R.
    "Clinical application of in situ tissue engineering using a scaffolding technique for reconstruction of the larynx and trachea."
    Annals of Otology, Rhinology & Laryngology 2008, 117, 673-678.
  10. Suzuki, T., Kobayashi, K., Tada, Y., Suzuki, Y., Wada, I., Nakamura, T., and Omori, K.
    "Regeneration of the trachea using bio-engineered scaffold with adipose-derived stem cells."
    Annals of Otology, Rhinology & Laryngology 2008, 117, 453-463.
  11. Tada, Y., Suzuki, T., Takezawa, T., Nomoto, Y., Kobayashi, K., Nakamura, T. and Omori, K.
    "Regeneration of trachea epithelium utilizing a novel bipotential collagen scaffold. "
    Annals of Otology, Rhinology & Laryngology 2008, 117, 359-365.
  12. Nomoto, Y., Kobayashi, K., Tada, Y., Wada, I., Nakamura, T. and Omori, K.
    "The effect of fibroblasts on epithelial regeneration on the surface of the bioengineered trachea. Effect of fibroblasts on epithelial regeneration on the surface of a bioengineered trachea. "
    Annals of Otology, Rhinology & Laryngology, 2008, 117, 59-64.
  13. Arakawa T, Kita Y, Niikura T
    "A rescue factor for Alzheimer's diseases: discovery, activity, structure, and mechanism"
    Curr.Med. Chem. 2008 15(21) 2086-98
  14. Arakawa T, kita Y, Ejima D, Gagnon P
    "Solvent modulation of column chromatography"
    Protein Pept.Lett. 2008 15(6) 544-55
  15. Arisaka F, Niikura T, Arakawa T, Kita Y
    "The structure analysis of Humanin analog, AGA-(C8R)HNG17, by circular dichroism and sedimentation equilibrium: Comparison with the parent molecule"
    Int.J. Biol. Macromol. 2008, 43, 88-93
  16. Kita Y, Niikura T, Arisaka F, Arakawa T
    "The Complex Structure Transition of Humanin Peptides by Sodium Dodecylsulfate and Trifluoroethanol"
    Protein Peptide Letters, 2008, 15, 510-515
  17. Arakawa T, Kita Y, Koyama AH
    "Solubility enhancement of gluten and organic compounds by arginine"
    Int. J. Pharm, 2008, 355, 220-223
  18. Arakawa T, Niikurat T, Arisaka F, Kita Y
    "Activity-dependent neurotrophic factor, ADNF, determines the structure characteristics of Colivelin, a fusion protein of ADNF9 and Humanin analog"
    J Pept Sci. 2008, 14, 631-636
  19. Yukutake Y, Tsuji S, Hirano Y, Adachi T, Takahashi T, Fujihara K, Agre P, Yasui M, Suematsu M.
    "Mercury chloride decreases the water permeability of aquaporin-4-reconstituted proteoliposomes."
    Biol Cell. 2008 ;100(6):355-63.
  20. K. Merrett, P. Fagerholm, C. R. McLaughlin, S. Dravida, N. Lagali1, N. Shinozaki, M. A. Watsky, R. Munger1, Y. Kato, F. Li1, C. J. Marmo and M. Griffith
    "Tissue Engineered Recombinant Human Collagen-based Corneal Substitutes for Implantation: Performance of Type I versus Type III Collagen "
    IOVS 49: 3887-3894, 2008

£PAGETOP

2007

  1. Arakawa, T., Niikura, T., Tajima, H., Arisaka, F., and Kita, Y.
    "Structure analysis of Activity-Dependent Neurotrophic Factor 9 by circular dichroism and sedimentation equilibrium."
    Journal of Molecular Neuroscience, in press.
  2. Arakawa, T., Tsumoto, K., Kita, Y., Chang, B., and Ejima, D.
    "Biotechnology applications of amino acids in protein purification  and formulations."
    Amino Acids,in press.
  3. Tsumoto, K., Ejima, A., Senczuk, M., Kita, Y., and Arakawa, T.
    "Effects of salts on protein-surface interactions: Applications for column chromatography."
    Journal of Pharmaceutical Science, in press.
  4. Arakawa, T., Ejima, D., Tsumoto, K., Obeyama, N., Tanaka, Y., Kita, Y., and Timasheff, S. N.
    "Suppression of protein interactions by arginine: a proposed mechanism of the arginine effects."
    Biophysical Chemistry, 127, 2007, 1-8.
  5. Arakawa, T., Tsumoto, K., Ejima, D., Kita, Y., Yonezawa, Y., and Tokunaga, M.
    "Induced binding of bovine serum albumin by ammonium sulfate in affinity and ion exchange colum chromatography."
    J. Biochem. Biophys Methods, 70, 2007, 493-498.
  6. Kobayashi, K., Nomoto, Y., Suzuki, T., Tada, Y., Miyake, M., Hazama, A., Nakamura, T. and Omori, K.
    "Potential of heterotopic fibroblasts as autologous transplanted cells for tracheal epithelial regeneration."
    Tissue engineering, 2007 [Epub ahead of print].
  7. N. Kato, M. Akai, l. Zulkifli, N. Matsuda, Y. Kato, S. Goshima, A. Hazama, M. Yamagami, H. R. Guy and N. Nobuyuki
    "Role of Positively Cahrged Amino Acids in the M2D Transmembrane Helix of Ktr/Trk/HKT Type Cation Transporters."
    Channels 1: 161-171, 2007

£PAGETOP

2006

  1. Nagase, H., Nagaoka, R., Takamiya, K., Huganir, R., Agre, P., and Yasui, M.
    "Molecular cloning and characterization of mouse aquaporin-6."
    Biochem. Biophys. Res. Commun. 352, 2006, 12-16.
  2. Beitz, E., Liu, K., Ikeda, M., Guggino, W.B., Agre, P., and Yasui, M.
    "Aquaporin-6--determinants of membrane trafficking in mammalian cells."
    Biol. Cell 98, 2006, 101-109.
  3. Nuriya, M. and Huganir, R. L.
    "Regulation of AMPA receptor trafficking by N-Cadherin."
    Journal of Neurochemistry, 97(3), 2006, 652-661.
  4. Nuriya, M., Jiang, J., Nemet, B., Eisenthal, K. B., and Yuste, R.
    "Imaging membrane potential in dendritic spines."
    Proceedings of National Academy of Science USA, 103(3), 2006, 786-790.
  5. Arakawa, T., Niikurat, T., Tajima, H., and Kita, Y.
    "The secondary structure analysis of anti-Alsheimer peptide, Humanin by circular dichroism"
    Journal of Peptide Science, 12, 2006, 639-642.
  6. Arakawa, T., Kita, Y., Ejima, D., Tsumoto, K., and Fukada, H.
    "Aggregation suppression of Proteins by arginine during thermal unfolding"
    Protein Pept. Lett. 13(6), 2006, 921-927.
  7. Arakawa, T., Ejima, D., Kita, Y., and Tsumoto, K.
    "Small molecule Pharmacological chaperones: From thermodynamic stabilization to pharmaceutical drugs"
    Biochim Biophys Acta, 1764, 2006, 1677-1687.
  8. Niikura, T., Tajima, H., and Kita, Y.
    "Neuronal cell death in Alzheimer's diseasse and a neuroprotective factor, Humanin"
    Current Neuropharmacology, 4, 2006, 139-147.
  9. Hayakawa, T., Hirano, Y., Makino, A., Michaud, S., Lagarde, M., Pegeaux, J.-F., Doutheau, A., Ito, K., Fujisawa, T., Takahashi, H., and Kobayashi, T.
    "Differential Membrane Packing of Stereoisomers of Bis(monoacylglycero)phosphate"
    Biochemistry, 45, 2006, 9198-9209.
  10. Kobayashi, K., Nomoto, Y., Suzuki, T., Tada, Y., Miyake, M., Hazama, A., Kanemaru, S., Nakamura, T., and Omori, K.
    "Effect of fibroblasts on tracheal epithelial regeneration in vitro."
    Tissue engineering 12, 2006, p2619-2628.
  11. Nomoto, Y., Suzuki, T., Tada, Y., Kobayashi, K., Miyake, M., Hazama, A., Wada, I., Kanemaru, S., Nakamura, T., and Omori, K.
    "Tissue engineering for regeneration of the tracheal epithelim."
    Annals of Otology, Rhinology, and Laryngology 115, 2006, 501-506.
  12. Otani, H., Matsuhisa, S., Akita, Y., Kyoi, S., Enoki, C., Tatsumi, K., Fujiwara, H., Hattori, R., Imamura, H., and Iwasaka, T.
    "Role of Mechanical Stress in the Form of Cardiomyocyte Death During the Early Phase of Reperfusion."
    Circ J. Vol.70, 2006, 1344-1355.

£PAGETOP

2005

  1. Ishikawa, Y., Zhenfang, Y., Inoue, N., Nakae, Y., Shono, M., Yasui, M., Skowronski, M. T., Nielsen, S., and Agre P.
    "Identification of aquaporin-5 in lipid rafts and its translocation to apical membranes by the activation of M3-muscarinic acetylcholine receptors in the interlobular ducts of rat parotid glands."
    Am. J. Physiol. 289, 2005, C1303-C1311.
  2. Liu, K., Kozono, D., Kato, Y., Agre, P., Hazama, A., and Yasui, M.
    "Conversion of aquaporin-6 from an anion channel to a water-selective channel by a single amino acid substitution."
    Proc. Natl. Acad. Sci. USA 102, 2005,2192-2197.
  3. Nuriya, M., Oh, S., and Huganir, R. L.
    "Phosphorylation dependent interactions of aActinin1/IQGAP1 with AMPA receptor subunit GluR4."
    Journal of Neurochemistry, 94(2), 2005, 544-552.
  4. Chiba, T., Yamada, M., Hashimoto, Y., Sato, M., Sasabe, J., Terashita, K., Aiso, S., Kita, Y., Matsuoka, M., and Nishimoto, I.
    "Development of a femtmolar-acting Humanin derivative named Colivelin by attached ADNF to its N terminus: characterization of Colivelin-mediated neuroprtection against Alzheimer's disease-relevant insults in vitro and in vivo."
    J. Neurosci. 25(44), 2005, 10252-10261.
  5. Yamada, M., Chiba, T., Sasabe, J., Nawa, M., Tajima, H., Niikura, T., Terashita, K., Aiso, S., Kita, Y., Matsuoka, M., and Nishimoto, I.
    "Implanted cannula-mediated repetitive administration of Abeta 25-35 into the mouse cerebral venticle effectively impairs spatial working memory."
    Behav Brain Res. Nov 7: 164(2), 2005, 139-146.
  6. Obata, Y., Niikura, T., Kanekura, K., Hashimoto, Y., Kawasumi, M., Kita, Y., Aiso, S., Matsuoka, M., and Nishimoto, I.
    "Expression of N19S-SOD1, a SOD1 mutant found in sporadic amyotrophic lateral sclerosis (ALS) patients, induced low-grade motoneuronal toxicity."
    J. Neurosci, Res. Nov 7: 164(2), 2005, 720-729.
  7. Tajima, H., Kawasumi, M., Chiba, T., Yamada, M., Yamashita, K., Nawa, M., Kita, Y., Kouyama, K., Aiso, S., Matsuoka, M., Niikura, T., and Nishimoto, I.
    "A Humanin derivative, S14G-HN, prevents amyloid-b-induced memory impairment in mice"
    J. Neurosci. Res. ,79, 2005, 714-23.
  8. Nagayoshi, C., Ishibashi, M., Kita, Y., Matsuoka, M., Nishimoto, I., and Tokunaga, M.
    "Expression, refolding and characterization of human brain serine racemase in Escherichia Coli with N-terminal  HIS-tag."
    Protein Pept. Lett.  4-9, 2005, 487-490.
  9. Hirano, Y., Shinmoto, N., Hata, M., Tsuda, M., and Hoshino, T.
    "Quantum chemical study on the deacylation step of human chymase"
    Journal of Molecular Structure: THEOCHEM, 757, 2005, 19-27.
  10. Hata, M., Hirano, Y., Hoshino, T., Nishida, R., and Tsuda, M.
    "Theoretical study on monooxygenation mechanism by chytochrome P450: an ultimate species in the substrate oxidation process"
    Journal of Molecular Structure: THEOCEM, 722, 2005, 133-137.
  11. Kobayashi, K., Fukunaga, S., Takenouchi, K., Kato-Mori, U., and Nakamura, F.
    "Functional role of type VI collagen during early feather development of the chick embryo in vitro."
    Animal Science Journal 76, 2005, 273-282.
  12. Ohashi, R., Takaya, J., Tsuji, S., Yamato, F., Hasui, M., Kinoshita, Y., and Kobayashi, Y.
    "Prognostic usefulness of lymphocyte V beta receptor determination in toxic shock syndrome."
    Eur J Pediatr. 164 2005:703-704.

£PAGETOP

2004

  1. Yasui, M.
    "Structure and Function of Aquaporins (Forum Minireview)."
    J. Pharmacol. Sci. 96, 2004,260-263.
  2. Beitz, E., Pavlovic-Djuranovic, S., Yasui, M., Agre, P., and Schultz, J.E.
    "Dissecting water and glycerol permeability of PfAQP, the aquaglyceroporin from Plasmodium falciparum."
    Proc. Natl. Acad. Sci. USA 101, 2004, 1153-1158.
  3. Gomes, A. R., Cunha, P., Nuriya, M., Faro, C. J., Huganir, R. L., Pires, E. V., Carvalho, A. L., and Duarte, C. B.
    "Metabotropic glutamate and dopamine receptors co-regulate AMPA receptor activity through PKA in cultured chick retinal neurones: effect on GluR4 phosphorylation and surface expression."
    Journal of Neurochemistry, 90(3), 2004, 673-682.
  4. Kanekura, K., Hashimoto, Y., Kita, Y., Sasabe, J., Aiso, S., Nishimoto, I., and Matsuoka, M.
    "A Rac1/ phosphatidylinositol-3 kinase /Akt3 anti-apoptotic pathway, triggered by alsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death"
    J. Biol. Chem., 280, 2004; 4532-4543.
  5. Chiba, T., Hashimoto, Y., Tajima, H., Yamada, M., Kato, R., Niikura, T., Terashita, K., Schulman, H., Aiso, S., Kita, Y., Matsuoka, M., Nishimoto, I.
    "Neuroprotective effect of activity-dependent neurotrophic factor, ADNF, agaist toxicity by familial amyotrophic lateral sclerosis-linked mutant SOD1 in vitro and in vivo."
    J. Neurosci. Res. 78, 2004, 542-552.
  6. Hashimoto, Y., Terashita, K., Niikurat, T., Yamagishi, Y., Ishisaka, M., Kanekura, K., Chiba, T., Yamada, M., Kita, Y., Aiso, S., Matsuoka, M., Nishimoto, I.
    "Humanin antagonists: dimerization-interfering mutants inhibit neuroprotection of Humanin."
    Eur. J. Neuroscie. 19, 2004, 2356-2364.
  7. Hashimoto, Y., Kaneko, Y., Tsukamoto, E., Frankowski, H., Kouyama, K., Kita, Y., Niikura, T., Aiso, S., Bredesen, D. E., Matsuoka, M., and Nishimoto, I.
    "Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-beta peptides via p75NTR/PLAIDD"
    J. Neurochem. 90, 2004, 549-558.
  8. Abe, Y., Hashimoto, Y., Tomita, Y., Terashita, K., Aiso, S., Tajima, H., Niikura, T., Matsuoka, M., and Nishimoto, I.
    "Cytotoxic mechanisms by M239V presenilin 2, a little analyzed Alzheimer's disease-causative mutant"
    Journal of Neuroscience Research, 77, 2004, 583-595.
  9. Okimoto, N., Nakamura, N., Suenega, A., Futatsugi, N., Hirano, Y., Yamaguchi, I., and Ebisuzaki, T.
    "Cooperative Motions of Protein and Hydration Water Molecules: Molecular Dynamics Study of Scytalone Dehydratase"
    Journal of American Chemical Society 126, 2004, 13132-13139.
  10. Hata, M., Hirano, Y., Hoshino, T., Nishida, R., and Tsuda, M.
    "Theoretical Study on Compound I Formation in Monooxygenation Mechanism by Cytochrome P450"
    Journal of Physical Chemistry B 108, 2004, 11189-11195.
  11. Suenaga, A., Kiyatkin, B., Hatakeyama, M., Futatsugi, N., Okimoto, N., Hirano, Y., Narumi, T., Kawai, A., Susukita, R., Taiji, M., Ebisuzaki, T., Hoek, J. B., Konagaya, A., and Kholodenko, B. N.
    "Tyr-317 Phosphorylation Increases Shc Structural Rigidity and Reduces Coupling of Domain Motions Remote from the Phosphorylation Site as Revealed by Molecular Dynamics Simulations"
    The Journal of Biological Chemistry 279, 2004 , 4657-4662.
  12. Kobayasi, K., Fukunaga, S., Takenouchi, K., and Nakamura, F.
    "Functional indispensability of fibronectin associated on the mesenchymal cell surface during the early period of feather development in the chick embryo in vitro. "
    Animal Science Journal 75, 2004, 441-449.
  13. Hasui, M., Sasaki, M., Tsuji, S., Yamamoto, A., Takaya, J., Taniuchi, S., Izumi, H., Hagihara, T., Daito, M., Kobayashi, Y.
    "Dental infections as a cause of persistent fever in a patient with chronic granulomatous disease."
    Clin Pediatr 43, 2004, 171-173.

£PAGETOP

2003

  1. Esteban, J. A., Shi, S. H., Wilson, C., Nuriya, M., Huganir, R. L., and Malinow, R.
    "PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity."
    Nature Neuroscience, 6(2), 2003, 136-143.
  2. Yokoyama, K., Ohtsuka, T., Kuraishi, C., Ono, K., Kita, Y., Arakawa, T., and Ejima, D.
    "Gelation of food protein induced by recombinant microbial transglutaminase"
    Journal of Food Science, 68 (1), 2003, 48-51.
  3. Yokoyama, K., Ejima, D., Kita, Y., Philo, J. S., and Arakawa, T.
    "Structure of folding intermediate at pH4.0 and native state of microbial transglutaminase"
    Biosci. Biotechnol Biochm. 67, 2003, 291-294.
  4. Terashita, K., Hashimoto, Y., Niikura, T., Tajima, H., Yamagishi, Y., Ishizsaka, M., Kawasumi, M., Chiba, T., Kanekura, K., Yamada, M., Nawa, M., Kita, Y., Aiso, S., and Nishimoto, I.
    "Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimerfs disease-related neurotoxicity: functional potentiation by isomerization and dimerization"
    J. Neurochem.85, 2003, 1521-1538.
  5. Abe, Y., Kouyama, K., Tomita, T., Tomita, Y., Ban, N., Nawa, M., Matsuoka, M., Niikura, T., Aiso, S., Kita, Y., Iwatsubo, T., and Nishimoto, I.
    "Analysis of neurons created from wild-type and Alzheimerfs mutation-knock-in ES cells by a highly efficient differentiation protocol"
    Journal of Neuroscience 23, 2003, 8513-8525.
  6. Zhu, Y., Miwa, Y., Yamanaka, Y., Yoda, T., Shibahara, M., Abe, Y., Sakurai, T., and Goto, K.
    "Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins"
    Journal of Pharmacological Science 92, 2003, 259-266.
  7. Kholmurodov, K., Hirano, Y., and Ebisuzaki, T.
    "MD Simulation of the Influence of Disease-Related Amino Acid Mutations in the Human Prion Protein"
    Chem-Bio Informatics Journal 3, 2003, 86-96.
  8. Okimoto, N., Yamanaka, K., Suenaga, A., Hirano, Y., Futatsugi, N., Narumi, T., Yasuoka, K., Susukita, R. Koishi, T., Frusawa, H., Kawai, A., Hata, M., Hoshino, T., and Ebisuzaki, T.
    "Molecular Dynamics Simulation of Prion Proteins |Effect of Ala117→Val mutation-"
    Chem-Bio Informatics Journal 3, 2003, 1-11.
  9. Komatsu, Y., Yukutake, Y., and Yoshid, M.
    "Four different clones of mouse anti-acetyllysine monoclonal antibodies having different recognition properties share a common immunoglobulin framework structure."
    J Immunol Meth. 272, 2003, 161-175.

£PAGETOP

2002

  1. Ikeda, M., Beitz, E., Kozono, D., Guggino, W.B., Agre, P., and Yasui, M.
    "Characterization of aquaporin-6 as a nitrate channel in mammalian cells: Requirement of pore-lining residue threonine-63."
    J. Biol. Chem. 277, 2002, 39873-39879.
  2. King, L. S. and Yasui, M.
    "Aquaporins and disease: lessons from mice and humans (review)."
    Trends Endocrin. Metab. 13(8), 2002,355-360.
  3. Hazama, A., Kozono, D., Guggino W. B., Agre, P., and Yasui, M.
    "Ion permeation of AQP6 water channel protein — single-channel recordings after Hg2+ activation."
    J. Biol. Chem. 277, 2002, 29224-29230.
  4. Kozono, D., Yasui, M., King, L. S., and Agre, P.
    "Aquaporin Water Channels: Atomic Structure and Molecular Dynamics meet Clinical Medicine (review)."
    J. Clin. Invest. 109, 2002, 1395-1399.
  5. Agre, P., King, L. S., Yasui, M., Guggino, W. B., Ottersen, O. P., Fujiyoshi, Y. Engel, A., and Nielsen, S.
    "Aquaporin Water Channels\From Atomic Structure to Clinical Medicine (review)."
    J. Physiol. 542, 2002, 3-16.
  6. Tajima, H., Niikura, T., Hashimoto, Y., Ito, Y., Kita, Y., Terashita, K., Yamazaki, K., Koto, A., Aiso, S., and Nishimoto, I.
    "Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease related insult"
    Neurosci. Lett. 324, 2002, 227-231.
  7. Kita, Y. and Arakawa, T.
    "Salts and Glycine increase reversibility and decrease aggregation during thermal unfolding of ribonuclease-A"
    Biosci, Biotechnol. Biochem, 66, 2002, 880-882.
  8. Hashimoto, H., Ito, Y., Arakawa, E., Kita, Y., Terashita, K., Niikura, T., and Nishimoto, I.
    "Neurotoxic mechanisms triggered by Alzheimer's disease-linked mutant M146L presenilin 1: involvement of NO synthase via a novel pertussis toxin target"
    J. Neurochem, 80(3), 2002, 426-437.
  9. Hashimoto, Y., Niikura, T., Ito, Y., Kita, Y., Terashita, K., and Nishimoto, I.
    "Neurotoxic mechanisus by Alzheimerfs disease-linked N141I mutant presenilin 2"
    J. Pharmacol Exp Ther, 300(3) 2002, 736-45.
  10. Hirano, Y., Hata, M., Hoshino, T., and Tsuda, M.
    "Quantum Chemical Study on the Catalytic Mechanism of C-subunit of cAMP-Dependent Protein Kinase"
    Journal of Physical Chemistry B 106, ,2002, 5788-5792.
  11. Nakamura, F., Seki, I., Kobayashi, K., Tanaka, M., and Fukunaga, S.
    "Immunohistochemical detection of cellular prion prorein (PrPc) in the rat central nervous system. "
    Animal Science Journal 73, 2002, 553-556.
  12. Taniuchi, S., Masuda, M., Hasui, M., Tsuji, S., Takahashi, H., and Kobayashi, Y.
    "Differential diagnosis and clinical course of autoimmune neutropenia in infancy: comparison with congenital neutropenia."
    Acta Paediatr. 91 2002, 1179-1182.
  13. Tsuji, S., Taniuchi, S., Hasui, M., Yamamoto, A., and Kobayashi, Y.
    "Increased nitric oxide production by neutrophils from patients with chronic granulomatous disease on trimethoprim-sulfamethoxazole."
    Nitric Oxide. 7, 2002, 283-288.
  14. Yamamoto, A., Taniuchi, S., Tsuji, S., Hasui, M., and Kobayashi, Y.
    "Role of reactive oxygen species in neutrophil apoptosis following ingestion of heat-killed Staphylococcus aureus."
    Clin Exp Immunol. 129 2002, 479-484.
  15. Hasui, M., Kotera, F., Tsuji, S., Yamamoto, A., Taniuchi, S., Fujikawa, Y., Nakajima, M., Yoshioka, A., and Kobayashi, Y.
    "Successful resumption of trimethoprim-sulfamethoxazole after oral desensitisation in patients with chronic granulomatous disease."
    Eur J Pediatr., 161 2002, 356357.

£PAGETOP

2001

  1. Agre, P., Borgnia, M. J., Yasui, M., Neely, J. D., Carbrey, J., Kozono, D., Beitz, E., Langloh, A. L., Hoffert, J., Leitch, V., and King, L. S.
    "Discovery of the aquaporins and their impact on basic and clinical physiology. Current Topics in Membranes."
    Hohmann, Nielsen, Agre, eds. 2001, 1-38.
  2. Hashimoto, Y., Niikura, T., Ito, Y., Sudo, H., Hata, M., Arakawa, E., Abe, Y., Kita, Y., and Nishimoto, I.
    "Detailed Characterization of Neuroprotection by a Rescue Factor Humanin against Various Alzheimer's Disease-Relevant Insults"
    J. Neurosci ,21, 2001, 9235-9245.
  3. Matsuda, S., Yasukawa, T., Homma, Y., Ito, Y., Niikura, T., Hiraki, T., Hirai, S., Ohno, S., Kita, Y., Kawasumi, M., Kouyama, K., Yamamoto, T., Kyriakis, J. M., and Nishimoto, I.
    "c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK."
    J. Neurosci. 21, 2001, 6597-607.
  4. Arakawa, T., Philo, J. S., and Kita, Y.
    "Kinetic and thermodynamic analysis of thermal unfolding of recombinant erythropoietin."
    Biosci Biotechnol Biochem. 65, 2001, 1321-1327.
  5. Wen, J., Zhang, M., Horan, T. P., Philo, J. S., Li, T., Wypych, J., Mendiaz, E. A., Langley, K. E., Aoki, K. H., Kuwamoto, M., Kita, Y., and Arakawa, T.
    "Copper staining method for extracting biologically active proteins from native gels."
    Biosci Biotechnol Biochem. 65, 2001, 1315-1320.
  6. Hashimoto, Y., Niikura, T., Tajima, H., Yasukawa, T., Sudo, H., Ito, Y., Kita. Y., Kawasumi, M., Kouyama, K., Doyu, M., Sobue, G., Koide, T., Tsuji, S., Lang, J., Kurokawa, K., Nishimoto, I.
    "A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta".
    Proc. Natl. Acad. Sci. USA, 98, 2001, 6336-6341.
  7. Hashimoto, Y., Niikura, T., Ito, Y., Sudo, H., Hata, M., Arakawa, E., Abe, Y., Kita, Y., and Nishimoto, I.
    "Detailed characterization of neuroprotection by a rescue factor humanin against various Alzheimer's disease-relevant insult"
    Journal of Neuroscience 21,2001, 9235-9245.
  8. Niikura, T., Hashimoto, Y., Okamoto, T., Abe Y., Yasukawa, T., Kawasumi, M., Hiraki, T., Kita, Y., Terashita, K., Kouyama, K., and Nishimoto, I.
    "Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimerfs V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner"
    Journal of Neuroscience 21, 2001, 1902-1910.
  9. Hata, M., Hirano, Y., Hoshino, T., and Tsuda, M.
    "Origin of the Primary Kinetic Hydrogen Isotope Effects on N-dealkylation from N-alkylamine by Hemoproteins"
    Bulletin of Chemical Society of Japan 74, 2001, 1577-1583.
  10. Hata, M., Hirano, Y., Hoshino, T., and Tsuda, M.
    "Monooxygenation Mechanism by Cytochrome P-450"
    Journal of American Chemical Society 123, 2001, 6410-6416.
  11. Taniuchi, S., Yamamura, S., Tsuji, S., Hasui, M., Ohtani, T., Nomura, S., and Kobayashi, Y.
    "A convenient method of granulocyte transfusion using a hydroxylethyl starch (HESPAN) containing a bag."
    Pediatr Hematol Oncol. 18, 2001, 299-301.
  12. Taniuchi, S., Masuda, M., Yamamoto, A., Hasui, M., Tsuji, S., Komiyama, Y., Takahashi, H., and Kobayashi, Y.
    "FcgammaRIII b and FcgammaRIIa polymorphism may affect the production of specific NA1 autoantibody and clinical course of autoimmune neutropenia of infancy."
    Hum Immunol., 62, 2001, 408-413.

£PAGETOP

2000

  1. Promeneur, D., Kwon, T-H., Yasui, M., Frokier, J., Knepper M. A., Agre, P. and Nielsen, S.
    "Dynamic Regulation of AQP6 expression in intercalated cells of rat kidney in response to altered acid/alkali load or water load."
    Am. J. Physiol. 279, 2000, F1014-F1026.
  2. Francis, P., Chung, J-J., Yasui, M., Berry, V., Moore, A., Wyatt, M.K., Wistow, G., Bhattacharya, S. and Agre, P.
    "Functional impairment of lens aquaporin in two families with dominantly inherited cataracts."
    Hum. Mol. Genet. 9 (15), 2000, 2329-2334.
  3. King, L. S., Yasui, M., and Agre, P.
    "Aquaporins in health and disease (review). "
    Molecular Medicine Today 6, 2000, 60-65.
  4. Beneken, J., Tu, J. C., Xiao, B., Nuriya, M., Yuan, J. P., Worley, P.F. and Leahy, D. J.
    "Structure of the Homer EVH1 Domain-Peptide Complex Reveals a New Twist in Polyproline Recognition."
    Neuron, 26, 2000, 143-154.
  5. Hagiwara, A., Hashimoto, Y., Niikura, T., Ito, Y., Terashita, K., Kita, Y., Nishimoto, I., and Umezawa, K.
    "Neuronal cell apoptosis by a receptor-binding domain peptide of apoE4 not through LDL receptor-related protein"
    Biochem Biophys Res Commun, 278, 2000, 633-639.
  6. Arakawa, T. and Kita, Y.
    "Protection of Bovine serum albumin from aggregation by Tween80"
    J. Pharm Sci 89 (5), 2000, 646-651.
  7. Arakawa, T. and Kita, Y.
    "Stability effects of Caprylate and acetyltryptophanate on heat-induced degradation of bovine serum albumin"
    Biochim. Biophys. Acta, 1479, 2000, 32-36.
  8. Arakawa, T. and Kita. Y.
    "Refractive Index of Proteins in organic solvents"
    Biochim. Biophys. Acta, 1479, 2000, 32-36.
  9. Hashimoto, Y., Jiang, H., Niikura, T., Ito, Y., Hagiwara, A., Umezawa K., Abe, Y., Murayama, Y., and Nishimoto, I.
    "Neuronal apoptosis by apolipoprotein E4 through low-density lipoprotein receptor-related protein and heterotrimeric GTPases"
    Journal of Neuroscience 20, 2000, 8401-8409.
  10. Abe, Y., Sakurai, T., Yamada, T., Nakamura, T., Yanagisawa, M., and Goto, K.
    "Functional analysis of five endothelin-B receptor mutations found in human Hirschsprung disease patients"
    Biochemical and Biophysical Research Communications 275, 2000, 524-531.
  11. Abe, Y., Nakayama, K., Yamanaka, A., Sakurai, T., and Goto, K.
    "Subtype-specific trafficking of endothelin receptor"
    Journal of Biological Chemistry 275, 2000, 8664-8671.
  12. Hirano, Y., Hata, M., Hoshino, T., and Tsuda, M.
    "Mechanism of phosphorylation of Ser residue catalysed by cAMP-dependent protein kinase"
    Japan Chemistry Program Exchange Journal 12(2), 2000, 119-128.
  13. Hirano, Y., Ohmori, N., Hata, M., N. Okimoto, Hoshino, T., and Tsuda, M.
    "The Importance of OH groups Containing Solid Films for High Sensitivity of Chemically Amplified Resists"
    Journal of Photopolymer Science and Technology 13, 2000, 503-506.
  14. Taniuchi, S., Masuda, M., Yamamoto, A., Hasui, M., Tsuji, S., Takahashi, H., and Kobayashi, Y.
    "Two cases of autoimmune neutropenia possibly induced by beta-lactam antibiotics in infants."
    J. Pediatr Hematol Oncol. 22, 2000, 533-538.
  15. Ohuchi, H., Suzuki, H., Toyohara, K., Tatsumi, K., Ono, Y., Arakaki, Y., and Echigo, S.
    "Abnormal cardiac autonomic nervous activity after right ventricular outflow tract reconstruction"
    Circulation. 102@2000, 2732-2738.

£PAGETOP

1999

  1. Yasui, M., Hazama, A., Kwon, T-H., and Nielsen, S., Guggino, W.B. and Agre, P.
    "Rapid gating and anion permeability of an intracellular aquaporin."
    Nature 402, 1999, 184-187.
  2. Yasui, M., Kwon, T-H., Knepper, M. A., Nielsen, S. and Agre, P.
    "Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia. Proc. Natl."
    Acad. Sci. USA 96, 1999, 5808-5813.
  3. Nishimoto, G., Zelenina, M., Li, D., Yasui, M., Aperia, A., Nielsen, S. and Nairn, A. C. "Arginine vasopressin stimulates phosphorylation of aquaporin-2 in rat renal tissue. Am."
    J. Physiol. 276, 1999, F254-F259.
  4. Caughey D-J. Narhi L. O., Kita, Y., Meng, S.-Y., Wen, E., Chen, W., Ratzkin, B., Fujimoto, J., Iwahara, T.,Yamamoto, T., and Arakawa, T.
    "Fraction of polyclonal antibodies to fragments of a neuro receptor using three increasingly chaotropic solvents"
    J. Chromatogr B Biomed Sci Appl 728 (1), 1999, 49-57.
  5. Hirano, Y., Ohmori, N., Hata, M., Hoshino, T., and Tsuda, M.
    "On the Origin of Photochemically Generated Protons in Polymethacrylate Films — A New Structure of Pag"
    Journal of Photopolymer Science and Technology 12, 1999, 637-640.
  6. Taniuchi, S., Yamamoto, A., Fujiwara, T., Hasui, M., Tsuji, S., and Kobayashi, Y.
    "Dizygotic twin sisters with myelokathexis: mechanism of its neutropenia."
    Am J Hematol. 62, 1999, 106-111.

£PAGETOP

1998

  1. Lecoin, L., Sakurai, T., Ngo, M.-T., Abe, Y., Yanagisawa, M., and Le Douarin, N. M.
    "Cloning and characterization of a novel endothelin receptor subtype in the avian class"
    Proceedings of the National Academy of Sciences of the USA, 95, 1998, 3024-3029.

£PAGETOP

1997

  1. Yasui, M., Srlachius, E., Lofgren, M., Belusa, R., Nielsen, S. and Aperia A.
    "Perinatal changes in expression of aquaporin-4 and other water and ion transporters in rat lung."
    J. Physiol. (London) 505, 1997, 3-11.
  2. Yasui, M., Zelenin, Z., Celsi, G. and Aperia, A.
    "Adenylate cyclase-coupled vasopressin receptor activates AQP2 promoter via a dual effect on CRE and AP1 elements."
    Am. J. Physiol. 272, 1997, F443-F450.
  3. Kita, Y. and Arakawa, T.
    "NDF and erbB2, erbB3 and erbB4"
    Experimental Medicine (Japanese), 15(9), 1997, 98-100.
  4. Narhi, L., Caughey, D.-J., Horan, T., Kita, Y., Chang, D. and Arakawa, T.
    "Fraction and Characterization of Polyclonal Antibodies using three Progressively More Chaotropic solvents"
    Analytical Biochem. 253(2), 1997, 246-252.

£PAGETOP